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WASHINGTON Adidas
Superstar Bloemen Goedkoop , April 30 (Xinhua) -- U.S. researchers
said Wednesday that it is possible to rebuild large amounts of muscles severely
damaged in traumatic accidents or military wounds by implanted tissues of pig
bladders.

Researchers from the University of Pittsburgh tested the experimental
technique on five male patients, who had lost between 58 and 90 percent of limb
muscle, and found that three of them had a 25 percent improvement in function.

"This new study is the first to show replacement of new functional muscle
tissue in humans, and we're very excited by its potential," Stephen
Badylak Adidas
Superstar Supercolor Goedkoop , senior investigator at the
University of Pittsburgh.

"These are patients who can't walk anymore, can't get out of a car, can't get
up and down from a chair, can't take steps without falling. Now we might have a
way of helping them get better," Badylak said.

Large amounts of muscle can be lost as a result of trauma www.superstarsgoedkoop.nl ,
such as a car accident, a sports injury, or even an explosive device. There is
no treatment for such volumetric muscle loss and native muscle is unable to
regenerate to that extent, to fully recovery function and tissue volume.
Instead, scar tissue can form to fill the gap.

Stem cells have been shown to help damaged tissue regenerate Adidas Superstar Goedkoop
kopen , but in most cases, stem cells should be taken out, isolated
and grown into the cell of choice, and then injected back into patients.

Badylak's team, however Adidas Superstar
Goedkoop , used the extracellular matrix (ECM) from pig bladders to
attract stem cells to the site of injury to promote regrowth of muscle.

According to the researchers, pig bladder ECM has been used for many years as
the basis for medical products for hernia repair and treatment of skin ulcers.
It is the biologic scaffold that remains left behind after cells have been
removed.

After first showing the ECM method worked in mice with severely injured hind
limbs, the researchers started a clinical trial involving five men, all at least
six months removed from the time of injury, and for whom surgery and physical
therapy had proved unsuccessful.

Three of the patients were in the military; two had thigh injuries from bombs
while one had an exercise-induced calf injury. The other two patients were
civilians with calf injuries from skiing accidents.

Before surgery Adidas
Superstar Slip On Trainer Wit Goedkoop , all patients completed a
12- to 16-week physical therapy program that focused specifically on their
individual functional deficits. The program continued until their function and
strength plateaued for a minimum of two weeks, with no signs of further
improvement.

Then, the researchers surgically implanted a "quilt" of compressed ECM sheets
designed to fill into their injury sites, and within 48 hours of the operation,
the participants resumed physical therapy for up to 26 additional weeks.

The researchers found that three participants Adidas
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who had thigh injuries and one who had a calf injury, were stronger by 25
percent six months after the surgery and that biopsies and scans all indicated
that muscle growth had occurred.

One thigh-injured patient improved on the "single hop test" by 1,820 percent,
and the other had a 352 percent improvement in a chair lift test and a 417
percent improvement in the single-leg squat test.

Two other participants with calf injuries did not have such dramatic results,
but both improved on at least one functional measure and said they felt better.

"This work represents an important step forward in our ability to repair
tissues and improve function with materials derived from natural proteins. There
will be more options to help our patients Heren
Adidas Superstar 80s Pioneers Pharrel Zwart Wit Goedkoop , " said
study co-author Peter Rubin, chair of the department of plastic surgery at the
University of Pittsburgh.

"We think it's remarkable that this approach was able to improve function
among patients who were all well past the acute injury response phase and were
not helped by the standard surgical procedures they had already had," Rubin
added.

The findings were published in the U.S. journal Science Translational
Medicine.

Floyd Mayweather Jr. (left) and Manny Pacquiao exchange punches during their
welterweight unification championship bout on Saturday at MGM Grand Garden Arena
in Las Vegas. Photo: CFP

Floyd Mayweather Jr. cemented his place among the pantheon of boxing greats
by improving to 48-0 with a unanimous decision over Manny Pacquiao on Saturday
in a fight that lived up to its immense hype and price tag.

Mayweather weathered an early assault by the Filipino southpaw and then won
the later rounds to finish ahead on all three judges' score cards in a
welterweight showdown that is expected to be the top grossing prize fight of all
time.

"When the history books are written, it was worth the wait," -Mayweather said
in the ring after a fight that was over five years in the -making.

Though Pacquiao repeatedly forced Mayweather to backpedal Adidas
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blunted his opponent's best efforts by using his renowned defensive skills while
-getting in several telling jabs and punches of his own.

Mayweather and Pacquiao had promised to deliver on years of hype and give
fans their money's worth and were true to their word in delivering everything
but a knockout.

"Manny Pacquiao is a hell of -fighter, I see now why he is at the pinnacle of
boxing," Mayweather said after an emotional embrace with Pacquiao. "I'm a smart
fighter, I outboxed him.

"We knew what we had to do. He's a tough competitor ... a very awkward
fighter and I had to take my time and watch him closely."

Mayweather is guaranteed at least a $120 million payday from the title bout
that had been dubbed the "Fight of the Century" and he said in the ring that his
next fight will be his last.

"My next fight in September will be my last and I will retire 49-0," said the
38-year-old American.

The 16 Adidas
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an MGM Grand Garden Arena in Las Vegas that.